The season's second week starts Thursday with an Atlantic Coast Conference matchup between Clemson and Georgia Tech. The Yellow Jackets are 4.5-point favorites.
Colorado is working on a short week, having played Colorado State on Sunday night. The Buffaloes jump back into the fray Friday when they travel to Toledo. Colorado is favored by 4.
One of the biggest games of the season takes place Saturday in Columbus. Ohio State entertains USC, with the Trojans favored by 6.5.
Other games of note: North Carolina (-4.5) at Connecticut; East Carolina at West Virginia (-6.5); Syracuse at Penn State (-28.5); Iowa (-6.5) at Iowa State; Mississippi State at Auburn (-14); Stanford at Wake Forest (-2.5); South Carolina at Georgia (-7); UCLA at Tennessee (-8); Purdue at Oregon (-12); Notre Dame (-3) at Michigan; Pittsburgh (-10.5) at Buffalo and Texas Christian (-11) at Virginia.
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